You may experience the following symptoms on a computer that is running Microsoft Exchange Server 2003 and Microsoft Exchange 2000 Server:
Incoming Simple Mail Transfer Protocol (SMTP) messages are delivered to e-mail recipients.
Outgoing SMTP messages remain in the outgoing message queue on the Exchange computer and are not delivered to some domains.
Note If you perform additional troubleshooting, you notice that mail is successfully delivered only to e-mail servers that advertise the Extended Simple Mail Transfer Protocol (ESMTP) CHUNKING verb. Examples of e-mail servers that advertise the CHUNKING verb include Exchange 2003 and Microsoft Exchange 2000 Server.
In Exchange Server 2003, the following event is logged in the Application log:
Event type: Warning Event source: MSExchangeTransport Event category: Connection Manager Event ID: 4000 Description: Message delivery to the remote domain 'remotesmtphost.com' failed for the following reason: The handle is invalid.
In Exchange 2000 Server, the following event is logged in the Application log:
Event type: Warning
Event source: smtpsvc
Event category: None
Event ID: 4000
Description: Message delivery to the remote domain ' remotesmtphost . com ' failed for the following reason: The handle is invalid.
Verify that the drive where the folder is located has sufficient hard disk space available.
Verify that the SYSTEM account has Full Control permissions assigned for the folder or that the SYSTEM account has at least Read permissions and Write permissions to the folder. To do this, follow these steps:
Start Windows Explorer, locate and then right-click the folder that the TEMP variable or the TMP variable points to, and then click Properties.
In the Temp Properties dialog box, click the Security tab, and then click SYSTEM in the Name list.
Verify that the Full Control check box is selected in the Allow column.
Note If the Full Control check box is not selected in the Allow column, verify that the Read check box in the Allow column is selected and that the Write check box in the Allow column is selected.
If you are running a file-level antivirus program, make sure that the antivirus program has not locked the files in the TEMP folder. For more information about how to do this, contact the antivirus program vendor.
For information about your hardware manufacturer, visit the following Web site: