The change is not applied until you reopen the database when you change a setting in Access 2007

Consider the following scenario. You open a Microsoft Office Access 2007 database. You change a setting in the Trust Center or in the Access Options dialog box. To apply the change, you must reopen the database. However, the database is not reopened automatically, and you do not receive a message that prompts you to reopen the database. In this scenario, the change is not applied. For example, if you change a macro setting in Access 2007 from Disable all macros with notification to Disable all macros without notification, the change is not applied until you close and then reopen the current database.

To resolve this behavior, manually close the database, and then reopen the database for the changes to take effect.

This behavior is by design.

To change a macro setting in the Trust Center, following these steps:

1. Click the Microsoft Office Button, and then click Access Options.
2. In the Access Options dialog box, click Trust Center in the left pane.
3. In the right pane, click Trust Center Settings.
4. In the Trust Center dialog box, click Macro Setting in the left pane.
5. Click to select a macro setting in the right panel.