Article ID: 937542 - View products that this article applies to.
Microsoft Forefront Security for Exchange Server notifications stop working if you change the Exchange Pickup folder path.
To resolve this problem, install Hotfix Rollup 1 for Forefront Security for Exchange Server.
For more information, click the following article number to view the article in the Microsoft Knowledge Base:
(http://support.microsoft.com/kb/936831/ )Description of Hotfix Rollup 1 for Microsoft Forefront Security for Exchange Server
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.