You can use the Text to Speech feature to hear selected text read aloud in a Microsoft Office for Mac file.
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If you have not already done so, set up the Text to Speech feature.
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On the Apple menu, click System Preferences.
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Click Accessibility > Speech.
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Select the voice that you want to use.
Tip: You can change the speed at which words are read by moving the Speaking Rate slider.
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Select the Speak selected text when the key is pressed check box, and then click Set Key to assign a keyboard shortcut that you want to use to hear text read aloud. The default keyboard shortcut is Option+Esc.
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In your Office file, select the text that you want to hear, and then press the keyboard shortcut.
See also
Keyboard shortcuts for Outlook
Use keyboard shortcuts to create PowerPoint presentations
Set up your device to work with accessibility in Microsoft 365