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When you are in a Skype call in Microsoft Skype for Business 2016, you may find you can't change the microphone or speaker volume by using Options > Audio Device. 


To fix this issue, install the  December 4, 2018, update (KB4461545) for Skype for Business 2016.

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After you install this update, you will receive a message that informs you that the change will take effect from the next call.

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