Consider the following scenario:
You install Cumulative Update 3 for BizTalk Server 2016 together with Feature Pack 1 (FP1).
You do not have Microsoft Visual Studio (VS) installed.
After the installation, you will receive an error message that resembles the following in the Administration Console:
Could not load file or assembly 'Microsoft.BizTalk.Analytics.Common, Version=18.104.22.168, Culture=neutral, PublicKeyToken=31bf3856ad364e35' or one of its dependencies. The system cannot find the file specified. (Microsoft.BizTalk.ExplorerOM)
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
This issue is fixed in the following cumulative update for BizTalk Server:
Cumulative Update 6 for BizTalk Server 2016
For information about the service packs and cumulative update list for BizTalk Server, see the following article in the Microsoft Knowledge Base:
2555976 Service pack and cumulative update list for BizTalk Server
For more information about BizTalk Server hotfixes, see the following article in the Microsoft Knowledge Base:
2003907 Information about BizTalk hotfixes and Cumulative Update support