Consider the following scenario:
- In a Microsoft Exchange Server 2007 environment, you have lots of accepted domains (15000 or more).
- You make changes to some accepted domains.
- HTTP Resource Not Found
- Post Data too large
This issue occurs because the whole accepted domain cache is reloaded from Active Directory directory service when you make changes on accepted domains. During this time, the accepted domain cache is locked to EWS requests.
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.