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Symptoms

Assume that you have read-only secondary replicas in Microsoft SQL Server 2016 AlwaysOn Availability Group (AG). When you use SQL Server Application roles in the replica for the first time, it works as expected. However, when you use them again, the Application roles may fail and you will receive the following error message:

Msg 3961, Level 16, State 1, Line Line Number
Snapshot isolation transaction failed in database '<DatabaseName>' because the object accessed by the statement has been modified by a DDL statement in another concurrent transaction since the start of this transaction. It is disallowed because the metadata is not versioned. A concurrent update to metadata can lead to inconsistency if mixed with snapshot isolation.

Resolution

This issue is fixed in the following cumulative update for SQL Server:

Cumulative update 4 for SQL Server 2016 SP2

Each new cumulative update for SQL Server contains all the hotfixes and all the security fixes that were included with the previous cumulative update. Check out the latest cumulative updates for SQL Server:

Latest cumulative update for SQL Server 2016

Status

Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.

References

Learn about the terminology Microsoft uses to describe software updates.

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