This will occur if you log on with a Standard User Account.
This is by design.
To execute commands from those registry keys, you must log in with an Administrator account. This issue effects only users with a Standard User account. If the user has an Administrator or Split Token, the execution proceeds.
See also: Description of the RunOnceEx Registry Key
Windows Server 2008 Enterprise, Windows Server 2008 Datacenter, Windows Server 2008 R2 Datacenter, Windows Server 2008 R2 Enterprise, Windows Server 2008 R2 Standard, Windows Server 2008 Standard, Windows Vista Business, Windows Vista Enterprise, Windows Vista Home Basic, Windows Vista Home Premium, Windows Vista Ultimate, Windows 7 Enterprise, Windows 7 Home Premium, Windows 7 Professional, Windows 7 Ultimate