In R12 of the Oracle eBusiness suite, Oracle added what they call "Access control feature in Oracle Applications Multiple Organizations." This change introduces an additional step in the initialization of the user context, and it breaks the functionality of the BizTalk EBS adapter.
Cumulative update information
The fix that resolves this issue is included in Cumulative Update 2 for BizTalk Server 2013 R2.
Note This hotfix adds a new Binding Property for WCF-OracleEBS Adapter to resolve this issue.
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
The third-party products that this article discusses are manufactured by companies that are independent of Microsoft. Microsoft makes no warranty, implied or otherwise, about the performance or reliability of these products.