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In Microsoft Internet Security and Acceleration (ISA) Server 2006, a memory leak occurs if the Enable caching of content received through the Background Intelligent Transfer Service (BITS) option is enabled in a cache rule.
To resolve this problem, apply the hotfix rollup package that is described in the following Microsoft Knowledge Base article:
940250 Description of the ISA Server 2006 hotfix package: date
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.