Symptoms
A natively installed .NET application may crash after the Microsoft Server Application Virtualization (Server App-V) client agent is installed on a computer.
Cause
This can occur if the application's .NET Configuration Settings File (.config) does not include the supportedRuntime element or the value specified for the element is not compatible with the version used by Server App-V.
Resolution
To work around this issue, modify the application's .config file and add <supportedRuntime version="v2.0.50727" /> under the <startup> node and restart the application.
More Information
For more information on the supportedRuntime element and the .NET configuration file schema see the following:
http://msdn.microsoft.com/en-us/library/w4atty68(v=VS.71).aspx