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Summary

This security update resolves a Microsoft Excel Remote Code Execution Vulnerability. To learn more about the vulnerability, see Microsoft Common Vulnerabilities and Exposures CVE-2021-28449.

Note: To apply this security update, you must have the release version of Microsoft Office 2016 installed on the computer.

Be aware that the update in the Microsoft Download Center applies to the Microsoft Installer (.msi)-based edition of Office 2016. It doesn't apply to the Office 2016 Click-to-Run editions, such as Microsoft Office 365 Home (see What version of Office am I using?). 

Known issue in this update

After you install this update, some automation add-ins for Excel might not load. This might generate a "Cannot run the macro" error message. To fix this issue, install KB 5001920.

How to get and install the update

Method 1: Microsoft Update

This update is available from Microsoft Update. When you turn on automatic updating, this update will be downloaded and installed automatically. For more information about how to get security updates automatically, see Windows Update: FAQ.

Method 2: Microsoft Update Catalog

To get the standalone package for this update, go to the Microsoft Update Catalog website.

Method 3: Microsoft Download Center

You can get the standalone update package through the Microsoft Download Center. Follow the installation instructions on the download page to install the update.

More information

Security update deployment information

For deployment information about this update, see Security update deployment information: April 13, 2021.

Security update replacement information

This security update replaces previously released security update 4493225.

File hash information

File name

SHA256 hash

mso2016-kb4504722-fullfile-x86-glb.exe

78917C813597BB5035E95D1EAD485294B983DDD44C04B53585D3908778425AD8

mso2016-kb4504722-fullfile-x64-glb.exe

C5DC73A15E8D42AB61D597586CB536FC3AD8CF30977D937B960D66382F345872

File information

The English (United States) version of this software update installs files that have the attributes that are listed in the following table. The dates and times for these files are listed in Coordinated Universal Time (UTC). The dates and times for these files on your local computer are displayed in your local time together with your current daylight saving time (DST) bias. Additionally, the dates and times may change when you perform certain operations on the files.

File identifier

File name

File version

File size

Date

Time

firstrun.exe

firstrun.exe

16.0.5149.1000

774440

23-Mar-21

11:59

msointl.dll.x86.1025

msointl.dll

16.0.4927.1000

3287904

23-Mar-21

07:15

msointl.dll.x86.1026

msointl.dll

16.0.4927.1000

1886048

23-Mar-21

07:15

msointl.dll.x86.1027

msointl.dll

16.0.4927.1000

1817952

23-Mar-21

07:34

msointl.dll.x86.1029

msointl.dll

16.0.4927.1000

1928032

23-Mar-21

07:15

msointl.dll.x86.1030

msointl.dll

16.0.4927.1000

1758040

23-Mar-21

07:15

msointl.dll.x86.1031

msointl.dll

16.0.4927.1000

1948216

23-Mar-21

07:15

msointl.dll.x86.1032

msointl.dll

16.0.4927.1000

2057048

23-Mar-21

07:15

msointl.dll.x86.3082

msointl.dll

16.0.4927.1000

1826360

23-Mar-21

07:15

msointl.dll.x86.1061

msointl.dll

16.0.4927.1000

1731664

23-Mar-21

07:15

msointl.dll.x86.1069

msointl.dll

16.0.4927.1000

1740640

23-Mar-21

07:34

msointl.dll.x86.1035

msointl.dll

16.0.4927.1000

1738504

23-Mar-21

07:15

msointl.dll.x86.1036

msointl.dll

16.0.4927.1000

1975360

23-Mar-21

07:15

msointl.dll.x86.1110

msointl.dll

16.0.4927.1000

1774648

23-Mar-21

07:34

msointl.dll.x86.1095

msointl.dll

16.0.4927.1000

1830688

23-Mar-21

07:34

msointl.dll.x86.1037

msointl.dll

16.0.4927.1000

2907936

23-Mar-21

07:15

msointl.dll.x86.1081

msointl.dll

16.0.4927.1000

1952312

23-Mar-21

07:15

msointl.dll.x86.1050

msointl.dll

16.0.4927.1000

1742088

23-Mar-21

07:15

msointl.dll.x86.1038

msointl.dll

16.0.4927.1000

1951584

23-Mar-21

07:15

msointl.dll.x86.1057

msointl.dll

16.0.4927.1000

1621848

23-Mar-21

07:15

msointl.dll.x86.1040

msointl.dll

16.0.4927.1000

1766240

23-Mar-21

07:15

msointl.dll.x86.1041

msointl.dll

16.0.4927.1000

2012512

23-Mar-21

07:15

msointl.dll.x86.1087

msointl.dll

16.0.4927.1000

2103648

23-Mar-21

07:15

msointl.dll.x86.1099

msointl.dll

16.0.4927.1000

1940320

23-Mar-21

07:35

msointl.dll.x86.1042

msointl.dll

16.0.4927.1000

2768736

23-Mar-21

07:15

msointl.dll.x86.1063

msointl.dll

16.0.4927.1000

1845808

23-Mar-21

07:15

msointl.dll.x86.1062

msointl.dll

16.0.4927.1000

1832016

23-Mar-21

07:15

msointl.dll.x86.1086

msointl.dll

16.0.4927.1000

1649232

23-Mar-21

07:15

msointl.dll.x86.1044

msointl.dll

16.0.4927.1000

1721624

23-Mar-21

07:15

msointl.dll.x86.1043

msointl.dll

16.0.4927.1000

1771264

23-Mar-21

07:15

msointl.dll.x86.1045

msointl.dll

16.0.4927.1000

1917280

23-Mar-21

07:15

msointl.dll.x86.1046

msointl.dll

16.0.4927.1000

1829656

23-Mar-21

07:15

msointl.dll.x86.2070

msointl.dll

16.0.4927.1000

1836312

23-Mar-21

07:15

msointl.dll.x86.1048

msointl.dll

16.0.4927.1000

1963064

23-Mar-21

07:15

msointl.dll.x86.1049

msointl.dll

16.0.4927.1000

1904384

23-Mar-21

07:15

msointl.dll.x86.1051

msointl.dll

16.0.4927.1000

1971552

23-Mar-21

07:15

msointl.dll.x86.1060

msointl.dll

16.0.4927.1000

1807712

23-Mar-21

07:15

msointl.dll.x86.2074

msointl.dll

16.0.4927.1000

1765936

23-Mar-21

07:15

msointl.dll.x86.9242

msointl.dll

16.0.4927.1000

1794912

23-Mar-21

07:15

msointl.dll.x86.1053

msointl.dll

16.0.4927.1000

1734912

23-Mar-21

07:15

msointl.dll.x86.1054

msointl.dll

16.0.4927.1000

1827376

23-Mar-21

07:15

msointl.dll.x86.1055

msointl.dll

16.0.4927.1000

1998680

23-Mar-21

07:15

msointl.dll.x86.1058

msointl.dll

16.0.4927.1000

1891896

23-Mar-21

07:16

msointl.dll.x86.1066

msointl.dll

16.0.4927.1000

2005552

23-Mar-21

07:16

msointl.dll.x86.2052

msointl.dll

16.0.4927.1000

2321704

23-Mar-21

07:16

msointl.dll.x86.1028

msointl.dll

16.0.4927.1000

2329384

23-Mar-21

07:16

msores.dll

msores.dll

16.0.4795.1000

81683304

16-Mar-21

06:34

msores.dll.x86

msores.dll

16.0.4795.1000

81683304

16-Mar-21

06:39

mso.dll.x86

mso.dll

16.0.5149.1000

14182256

23-Mar-21

11:59

msointl.dll.x86.1033

msointl.dll

16.0.4927.1000

1539640

16-Mar-21

06:33

File identifier

File name

File version

File size

Date

Time

firstrun.exe

firstrun.exe

16.0.5149.1000

816928

23-Mar-21

11:58

msointl.dll.x64.1025

msointl.dll

16.0.5149.1000

3324768

24-Mar-21

12:28

msointl.dll.x64.1026

msointl.dll

16.0.5149.1000

1910112

24-Mar-21

12:04

msointl.dll.x64.1027

msointl.dll

16.0.5149.1000

1842064

24-Mar-21

12:21

msointl.dll.x64.1029

msointl.dll

16.0.5149.1000

1952112

24-Mar-21

12:28

msointl.dll.x64.1030

msointl.dll

16.0.5149.1000

1782112

24-Mar-21

12:28

msointl.dll.x64.1031

msointl.dll

16.0.5149.1000

1972608

24-Mar-21

12:28

msointl.dll.x64.1032

msointl.dll

16.0.5149.1000

2081672

24-Mar-21

12:28

msointl.dll.x64.3082

msointl.dll

16.0.5149.1000

1850736

24-Mar-21

12:28

msointl.dll.x64.1061

msointl.dll

16.0.5149.1000

1755480

24-Mar-21

12:04

msointl.dll.x64.1069

msointl.dll

16.0.5149.1000

1764704

24-Mar-21

12:21

msointl.dll.x64.1035

msointl.dll

16.0.5149.1000

1762688

24-Mar-21

12:28

msointl.dll.x64.1036

msointl.dll

16.0.5149.1000

1999256

24-Mar-21

12:28

msointl.dll.x64.1110

msointl.dll

16.0.5149.1000

1799008

24-Mar-21

12:22

msointl.dll.x64.1095

msointl.dll

16.0.5149.1000

1854816

24-Mar-21

12:22

msointl.dll.x64.1037

msointl.dll

16.0.5149.1000

2944840

24-Mar-21

12:28

msointl.dll.x64.1081

msointl.dll

16.0.5149.1000

1976664

24-Mar-21

12:28

msointl.dll.x64.1050

msointl.dll

16.0.5149.1000

1766232

24-Mar-21

12:28

msointl.dll.x64.1038

msointl.dll

16.0.5149.1000

1975664

24-Mar-21

12:04

msointl.dll.x64.1057

msointl.dll

16.0.5149.1000

1645968

24-Mar-21

12:04

msointl.dll.x64.1040

msointl.dll

16.0.5149.1000

1790864

24-Mar-21

12:28

msointl.dll.x64.1041

msointl.dll

16.0.5149.1000

2036568

24-Mar-21

12:28

msointl.dll.x64.1087

msointl.dll

16.0.5149.1000

2128216

24-Mar-21

12:28

msointl.dll.x64.1099

msointl.dll

16.0.5149.1000

1964416

24-Mar-21

12:22

msointl.dll.x64.1042

msointl.dll

16.0.5149.1000

2793336

24-Mar-21

12:28

msointl.dll.x64.1063

msointl.dll

16.0.5149.1000

1869712

24-Mar-21

12:28

msointl.dll.x64.1062

msointl.dll

16.0.5149.1000

1855872

24-Mar-21

12:28

msointl.dll.x64.1086

msointl.dll

16.0.5149.1000

1673600

24-Mar-21

12:04

msointl.dll.x64.1044

msointl.dll

16.0.5149.1000

1745256

24-Mar-21

12:28

msointl.dll.x64.1043

msointl.dll

16.0.5149.1000

1795416

24-Mar-21

12:28

msointl.dll.x64.1045

msointl.dll

16.0.5149.1000

1941344

24-Mar-21

12:28

msointl.dll.x64.1046

msointl.dll

16.0.5149.1000

1853792

24-Mar-21

12:28

msointl.dll.x64.2070

msointl.dll

16.0.5149.1000

1860440

24-Mar-21

12:28

msointl.dll.x64.1048

msointl.dll

16.0.5149.1000

1986904

24-Mar-21

12:28

msointl.dll.x64.1049

msointl.dll

16.0.5149.1000

1928024

24-Mar-21

12:28

msointl.dll.x64.1051

msointl.dll

16.0.5149.1000

1996128

24-Mar-21

12:04

msointl.dll.x64.1060

msointl.dll

16.0.5149.1000

1832280

24-Mar-21

12:04

msointl.dll.x64.2074

msointl.dll

16.0.5149.1000

1790296

24-Mar-21

12:28

msointl.dll.x64.9242

msointl.dll

16.0.5149.1000

1818968

24-Mar-21

12:28

msointl.dll.x64.1053

msointl.dll

16.0.5149.1000

1759072

24-Mar-21

12:28

msointl.dll.x64.1054

msointl.dll

16.0.5149.1000

1851224

24-Mar-21

12:28

msointl.dll.x64.1055

msointl.dll

16.0.5149.1000

2023264

24-Mar-21

12:28

msointl.dll.x64.1058

msointl.dll

16.0.5149.1000

1915736

24-Mar-21

12:28

msointl.dll.x64.1066

msointl.dll

16.0.5149.1000

2029920

24-Mar-21

12:04

msointl.dll.x64.2052

msointl.dll

16.0.5149.1000

2346272

24-Mar-21

12:28

msointl.dll.x64.1028

msointl.dll

16.0.5149.1000

2353960

24-Mar-21

12:28

msointl.dll.x86.1025

msointl.dll

16.0.4927.1000

3287904

23-Mar-21

07:15

msointl.dll.x86.1026

msointl.dll

16.0.4927.1000

1886048

23-Mar-21

07:15

msointl.dll.x86.1029

msointl.dll

16.0.4927.1000

1928032

23-Mar-21

07:15

msointl.dll.x86.1030

msointl.dll

16.0.4927.1000

1758040

23-Mar-21

07:15

msointl.dll.x86.1031

msointl.dll

16.0.4927.1000

1948216

23-Mar-21

07:15

msointl.dll.x86.1032

msointl.dll

16.0.4927.1000

2057048

23-Mar-21

07:15

msointl.dll.x86.3082

msointl.dll

16.0.4927.1000

1826360

23-Mar-21

07:15

msointl.dll.x86.1061

msointl.dll

16.0.4927.1000

1731664

23-Mar-21

07:15

msointl.dll.x86.1035

msointl.dll

16.0.4927.1000

1738504

23-Mar-21

07:15

msointl.dll.x86.1036

msointl.dll

16.0.4927.1000

1975360

23-Mar-21

07:15

msointl.dll.x86.1037

msointl.dll

16.0.4927.1000

2907936

23-Mar-21

07:15

msointl.dll.x86.1081

msointl.dll

16.0.4927.1000

1952312

23-Mar-21

07:15

msointl.dll.x86.1050

msointl.dll

16.0.4927.1000

1742088

23-Mar-21

07:15

msointl.dll.x86.1038

msointl.dll

16.0.4927.1000

1951584

23-Mar-21

07:15

msointl.dll.x86.1057

msointl.dll

16.0.4927.1000

1621848

23-Mar-21

07:15

msointl.dll.x86.1040

msointl.dll

16.0.4927.1000

1766240

23-Mar-21

07:15

msointl.dll.x86.1041

msointl.dll

16.0.4927.1000

2012512

23-Mar-21

07:15

msointl.dll.x86.1087

msointl.dll

16.0.4927.1000

2103648

23-Mar-21

07:15

msointl.dll.x86.1042

msointl.dll

16.0.4927.1000

2768736

23-Mar-21

07:15

msointl.dll.x86.1063

msointl.dll

16.0.4927.1000

1845808

23-Mar-21

07:15

msointl.dll.x86.1062

msointl.dll

16.0.4927.1000

1832016

23-Mar-21

07:15

msointl.dll.x86.1086

msointl.dll

16.0.4927.1000

1649232

23-Mar-21

07:15

msointl.dll.x86.1044

msointl.dll

16.0.4927.1000

1721624

23-Mar-21

07:15

msointl.dll.x86.1043

msointl.dll

16.0.4927.1000

1771264

23-Mar-21

07:15

msointl.dll.x86.1045

msointl.dll

16.0.4927.1000

1917280

23-Mar-21

07:15

msointl.dll.x86.1046

msointl.dll

16.0.4927.1000

1829656

23-Mar-21

07:15

msointl.dll.x86.2070

msointl.dll

16.0.4927.1000

1836312

23-Mar-21

07:15

msointl.dll.x86.1048

msointl.dll

16.0.4927.1000

1963064

23-Mar-21

07:15

msointl.dll.x86.1049

msointl.dll

16.0.4927.1000

1904384

23-Mar-21

07:15

msointl.dll.x86.1051

msointl.dll

16.0.4927.1000

1971552

23-Mar-21

07:15

msointl.dll.x86.1060

msointl.dll

16.0.4927.1000

1807712

23-Mar-21

07:15

msointl.dll.x86.2074

msointl.dll

16.0.4927.1000

1765936

23-Mar-21

07:15

msointl.dll.x86.9242

msointl.dll

16.0.4927.1000

1794912

23-Mar-21

07:15

msointl.dll.x86.1053

msointl.dll

16.0.4927.1000

1734912

23-Mar-21

07:15

msointl.dll.x86.1054

msointl.dll

16.0.4927.1000

1827376

23-Mar-21

07:15

msointl.dll.x86.1055

msointl.dll

16.0.4927.1000

1998680

23-Mar-21

07:15

msointl.dll.x86.1058

msointl.dll

16.0.4927.1000

1891896

23-Mar-21

07:16

msointl.dll.x86.1066

msointl.dll

16.0.4927.1000

2005552

23-Mar-21

07:16

msointl.dll.x86.2052

msointl.dll

16.0.4927.1000

2321704

23-Mar-21

07:16

msointl.dll.x86.1028

msointl.dll

16.0.4927.1000

2329384

23-Mar-21

07:16

conversion.office.msores.dll

msores.dll

16.0.4795.1000

81683088

16-Mar-21

06:32

msores.dll

msores.dll

16.0.4795.1000

81683088

16-Mar-21

06:32

ppt.conversion.msores.dll

msores.dll

16.0.4795.1000

81683088

ppt.edit.msores.dll

msores.dll

16.0.4795.1000

81683088

wac.office.msores.dll

msores.dll

16.0.4795.1000

81683088

msores.dll

msores.dll

16.0.4795.1000

81683304

16-Mar-21

06:32

msores.dll.x86

msores.dll

16.0.4795.1000

81683304

16-Mar-21

06:39

mso.dll.x64

mso.dll

16.0.5149.1000

19876200

23-Mar-21

11:58

mso.dll.x86

mso.dll

16.0.5149.1000

14182256

23-Mar-21

11:59

msointl.dll.x64.1033

msointl.dll

16.0.4927.1000

1564424

16-Mar-21

06:33

msointl.dll.x86.1033

msointl.dll

16.0.4927.1000

1539640

16-Mar-21

06:33

Information about protection and security

Protect yourself online: Windows Security support

Learn how we guard against cyber threats: Microsoft Security

Change history

 The following table summarizes some of the most important changes to this topic.

Date

Description

April 23, 2021

Added a "Known issue in this update" section to describe an issue that users may experience after installing this update.

May 11, 2021

Updated the "Known issue in this update" section to provide a resolution to the issue.

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