MSExchangeMapiMailboxAppPool causes prolonged 100% CPU in Exchange Server 2019 and 2016

Symptoms

In Microsoft Exchange Server 2019 and Exchange Server 2016, threads of MSExchangeMapiMailboxAppPool are stuck in lock contention (clr!AwareLock::Contention), which causes the affected server to stop responding with 100% CPU usage for a long time (1+ hour).

Resolution

To fix this issue, install one of the following updates:

For Exchange Server 2019, install the Cumulative Update 7 for Exchange Server 2019 or a later cumulative update for Exchange Server 2019.​
For Exchange Server 2016, install the Cumulative Update 18 for Exchange Server 2016 or a later cumulative update for Exchange Server 2016.

References

Learn about the  terminology that Microsoft uses to describe software updates.

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