Symptoms
Consider the following scenario:
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You use a map in a Microsoft BizTalk Server project to do transformations.
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Multiple destination schemas are used in the map.
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One of the schemas is blank.
In this scenario, you receive an error message that resembles the following:
Error: Invalid input/output document into/from the transform. Does not have a single root node.
Resolution
Cumulative update information
The fix for this issue is included in Cumulative Update 2 for BizTalk Server 2013 R2.
Status
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
References
Learn about service pack and cumulative update list for BizTalk Server. Learn about BizTalk Server hotfixes and cumulative update support.