When using the Exchange Management Console from a Hub-Transport server on Exchange 2007, you will get the following errors when you try to manage a remote Client Access Server.
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Microsoft Exchange Error
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The following error(s) were reported while loading topology information:
Get-ActiveSyncVirtualDirectory
Failed
Error:
An error occurred while trying to access IIS (Internet Information Service)
metabase. Make sure the Internet Information Service Manager component is installed
and configured properly.
Unknown error (0x80005000)
Get-OabVirtualDirectory
Failed
Error:
An error occurred while trying to access IIS (Internet Information Service)
metabase. Make sure the Internet Information Service Manager component is installed
and configured properly.
Unknown error (0x80005000)
Get-OWAVirtualDirectory
Failed
Error:
An error occurred while trying to access IIS (Internet Information Service)
metabase. Make sure the Internet Information Service Manager component is installed
and configured properly.
Unknown error (0x80005000)
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Symptoms
This is because you don’t have the IIS management binaries installed on the HUB server. These binaries are not needed for the management console to work on the HUB server itself, but they are required for doing remote administration on a CAS server.
Cause
Open the Command prompt on the server and run the following commands to be run on Hub-Transport server
ServerManagerCmd -i Web-Server
ServerManagerCmd -i Web-ISAPI-Ext
ServerManagerCmd -i Web-Metabase
ServerManagerCmd -i Web-Lgcy-Mgmt-Console
ServerManagerCmd -i Web-Basic-Auth
ServerManagerCmd -i Web-Digest-Auth
ServerManagerCmd -i Web-Windows-Auth
ServerManagerCmd -i Web-Dyn-Compression
Ref: How to install the Windows Server 2008 operating system prerequisites for Client Access servers
Reboot the Hub Transport server and open the Exchange Management Console. You should now be able to access the Client Access Server without any issues