Consider the following scenario:
You install Microsoft Forefront Threat Management Gateway (TMG) 2010 on a computer.
You enable the Email Protection feature in Forefront TMG 2010.
You install Microsoft Exchange Server 2010 Service Pack (SP1) on the computer.
In this scenario, the Microsoft Forefront TMG Managed Control (IsaManagedCtrl) service does not start, and you receive an instance of the 0x80131500 error.
This issue occurs because TMG depends on the anti-spam cmdlets that are removed by Exchange Server 2010 SP1. Therefore, TMG Managed Control service cannot start.
The TMG Managed Control (IsaManagedCtrl) service uses the Get-AntispamUpdates cmdlets to generate snapshots of the Forefront Protection for Exchange (FPE) configuration. Additionally, the service uses the cmdlets to show the Update status on the Update Center Properties page of the Forefront TMG Management console.
To resolve this issue, install the software update that is described in the following Microsoft Knowledge Base (KB) article:
2433623 Software Update 2 for Microsoft Forefront Threat Management Gateway (TMG) 2010 Service Pack 1
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
For more information about software update terminology, click the following article number to view the article in the Microsoft Knowledge Base:
824684 Description of the standard terminology that is used to describe Microsoft software updates