The Microsoft.BizTalk.Edi.BatchingOrchestration.BatchingService orchestration performance is decreased over time, and there's a backlog in the BizTalkMsgBoxDb Spool and InstanceStateMessageReferences_<HOST> tables.
This issue is more prominent when the following conditions are true:
The EDI Batching termination criteria is configured to let the orchestration instance run longer.
The EDI Batching release criteria is configured to release the outgoing batch more frequently.
There's a large load of messages being processed by EDI BatchingService orchestration.
Cumulative update information
For BizTalk Server 2013 R2
The fix that resolves this issue is included in Cumulative Update 5 for BizTalk Server 2013 R2.
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
Learn about service pack and cumulative update list for BizTalk Server.
Learn about BizTalk Server hotfixes and cumulative update support.