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When a BizTalk HTTP send port times out, the host instance that the send port is running in may terminate. When this issue occurs, you may see error messages that resemble the following:

Log Name:      Application
Source:        BizTalk Server
Event ID:      5743
The adapter failed to transmit message going to send port "MySendPort" with URL "http://webserver/myapp.aspx". It will be retransmitted after the retry interval specified for this Send Port. Details:"The HTTP send adapter cannot complete the transmission within the specified time. 
 Destination: http://webserver/myapp.aspx ".
Log Name:      Application
Source:        .NET Runtime
Event ID:      1026
Application: BTSNTSvc.exe
Framework Version: v4.0.30319
Description: The process was terminated due to an unhandled exception.
Exception Info: System.InvalidOperationException
   at Microsoft.BizTalk.HttpTransport.HttpAsyncTransmitter.FireTransmitComplete(System.Exception)
   at Microsoft.BizTalk.HttpTransport.HttpAsyncTransmitter.TimeoutCallback(System.Object, Boolean)
   at System.Threading._ThreadPoolWaitOrTimerCallback.WaitOrTimerCallback_Context(System.Object, Boolean)
   at System.Threading._ThreadPoolWaitOrTimerCallback.WaitOrTimerCallback_Context_t(System.Object)
   at System.Threading.ExecutionContext.RunInternal(System.Threading.ExecutionContext, System.Threading.ContextCallback, System.Object, Boolean)
   at System.Threading.ExecutionContext.Run(System.Threading.ExecutionContext, System.Threading.ContextCallback, System.Object, Boolean)
   at System.Threading._ThreadPoolWaitOrTimerCallback.PerformWaitOrTimerCallback(System.Object, Boolean)
Log Name:      Application
Source:        Application Error
Event ID:      1000
Faulting application name: BTSNTSvc.exe, version:, time stamp: 0x538aea40
Faulting module name: KERNELBASE.dll, version: 6.2.9200.17637, time stamp: 0x5697fdbe
Exception code: 0xe0434352
Fault offset: 0x00010192
Faulting process id: 0x2c18
Faulting application start time: 0x01d1a544c0a2cd2a
Faulting application path: C:\Program Files (x86)\Microsoft BizTalk Server 2013 R2\BTSNTSvc.exe
Faulting module path: C:\Windows\SYSTEM32\KERNELBASE.dll
Report Id: 0b5ba136-1168-11e6-943e-005056b26aca
Faulting package full name: 
Faulting package-relative application ID


Cumulative update information

The fix that resolves this issue is included in the following cumulative update for BizTalk Server:


Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.


Learn about the service pack and cumulative update list for BizTalk Server.

Learn about BizTalk Server hotfixes and cumulative update support.

The third-party products that this article discusses are manufactured by companies that are independent of Microsoft. Microsoft makes no warranty, implied or otherwise, about the performance or reliability of these products.

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