If BizTalk default group name is changed, management pack is unable to discover BizTalk installation.
When group name is changed, you can change the group name in database, but fail to change the registry and BTSNTSvc service command parameters on all runtime machines. Because of the mismatch in name between registry and database, BizTalk installation discovery fails.
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
This problem is fixed in the following cumulative update for BizTalk Server:
Cumulative Update 1 for BizTalk Server 2020
For information about the service packs and cumulative update list for BizTalk Server, see the following article in the Microsoft Knowledge Base:
2555976 Service pack and cumulative update list for BizTalk Server
For more information about BizTalk Server hotfixes, see the following article in the Microsoft Knowledge Base:
2003097 Information about BizTalk hotfixes and Cumulative Update support