Consider the following scenario:
You use a dynamic send port in BizTalk Server.
You configure the port to specify the send handlers for one or more adapters.
The send handlers that you have selected are not the default send handlers for at least one of the adapters.
In this case, when you export the port bindings and import them into another BizTalk environment, you may notice that the send handler configuration is not imported. Instead, the handlers are set to the default send handlers for each adapter.
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
This problem is fixed in the following cumulative update for BizTalk Server:
Cumulative Update 8 for BizTalk Server 2016
For information about the service packs and cumulative update list for BizTalk Server, see the following article in the Microsoft Knowledge Base:
2555976 Service pack and cumulative update list for BizTalk Server
For more information about BizTalk Server hotfixes, see the following article in the Microsoft Knowledge Base:
2003907 Information about BizTalk hotfixes and Cumulative Update support