Microsoft BizTalk host instances and the Admin console don't start if the default web proxy is disabled. For example, a configuration file, such as BTSNTSvc.exe.config or machine.config, contains the following setting:
<defaultProxy enabled="False" />
In this situation, you receive the following error message:
Error source: Microsoft.BizTalk.CommonSettings
Error description: The type initializer for 'Microsoft.BizTalk.CommonSettings.CBizTalkSettingsLookup' threw an exception.
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
This problem is fixed in the following cumulative update for BizTalk Server:
Cumulative Update 2 for BizTalk Server 2020
For information about the service packs and cumulative update list for BizTalk Server, see the following article in the Microsoft Knowledge Base:
2555976 Service pack and cumulative update list for BizTalk Server
For more information about BizTalk Server hotfixes, see the following article in the Microsoft Knowledge Base:
2003097 Information about BizTalk hotfixes and Cumulative Update support