Symptoms
When this issue occurs, you may experience a connectivity issue. Additionally, the following events are logged in the Application Log:
Event id 4999: Event id 1000: Event id 7301:Event id 7036:Cause
This is a known issue in Microsoft Exchange 2010 Information Store.
Resolution
To fix this issue, installĀ Update Rollup 11 for Exchange Server 2010 Service Pack 3.
Status
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.