Symptoms
Assume that you set your computer that has multiple monitors to non-recommended dots per inch (DPI). When you use Microsoft Skype for Business 2016 to share an application, and then switch to share a monitor, the client is forced into a DPI awareness that does not scale correctly within the current DPI setting.
Resolution
To fix this issue, install the May 9, 2017, security update (KB3191858) for Skype for Business 2016.