Symptoms
After you upgrade to Microsoft Exchange Server 2016 CU7, you may notice that the Exchange mailbox transport delivery service is unable to start. Additionally, transport service (edgetransport.exe) crashes and returns the following error message:
Note
ID: 4999
Level: Error
Source: MSExchange Common
Message: Watson report about to be sent for process id: xxxxx, with parameters: E12IIS, c-RTL-AMD64, 15.01.1261.035, edgetransport, mscorlib, M.W.RegistryKey.CreateSubKeyInternal, System.UnauthorizedAccessException
Cause
This problem occurs because permission isn't handled correctly when accessing some components.
Resolution
To fix this problem, install Cumulative Update 10 for Exchange Server 2016 or a later cumulative update for Exchange Server 2016.
Status
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
References
Learn about the terminology that Microsoft uses to describe software updates.