Assume that you are using MQSeries adapter receive location (RL) in Microsoft BizTalk Server. After you install BizTalk Server 2013 R2 cumulative update 5 (CU5), and restart the IBM WebSphere MQ server, the MQSeries receive location fails to recover automatically.
This issue occurs because of a regression issue in the BizTalk Server 2013 R2 CU5 MQSeries fixes where it does not handle this error anymore.
Microsoft has confirmed that this is a problem in the Microsoft products that are listed in the "Applies to" section.
For information about the service packs and cumulative update list for BizTalk Server, click the following article number to view the article in the Microsoft Knowledge Base:
2555976 Service Pack and cumulative update list for BizTalk Server
For more information about BizTalk Server hotfixes, click the following article number to view the article in the Microsoft Knowledge Base:
2003907 Information about BizTalk hotfixes and Cumulative Update support