Outlook and mobile clients don’t authenticate after November 2021 fixes for Windows installed

Applies To
Exchange Server 2019 Exchange Server 2016 Exchange Server 2013 Exchange Server 2010

Symptoms

In a Microsoft Exchange Server 2019, 2016, 2013, or 2010 on-premises environment that’s configured to use Kerberos for authentication, the Microsoft Outlook and mobile device clients continually prompt for authentication after you install the November 2021 Windows Server update on domain controllers to fix the problem that's described in security advisory CVE-2021-42278.

Resolution

An out-of-band Windows update is available to resolve this problem. Install the following fix on domain controllers, as appropriate for your system version.
 

OS Resolving KB article
Windows 10, version 1809
Windows Server 2019
5008602
Windows 10, version 1607
Windows Server 2016
5008601
Windows Server 2012 R2 5008603
Windows Server 2012 5008604
Windows Server 2008 R2 5008605
Windows Server 2008 5008606