Follow these steps to temporarily turn off real-time Microsoft Defender antivirus protection in Windows Security. However, keep in mind that if you do, your device may be vulnerable to threats.
Select Start > Settings > Update & Security > Windows Security > Virus & threat protection > Manage settings (or Virus & threat protection settings in previous versions of Windows 10).
Switch Real-time protection to Off. Note that scheduled scans will continue to run. However, files that are downloaded or installed will not be scanned until the next scheduled scan.